I have been meaning to pass on a series of articles related to the issues dyslexia causes for some time now. The series was published a couple of years ago, and Roger Johansson blogged about it a couple of weeks ago, bringing the series back to mind.
Dyslexia pretty much flummoxes me, so I'll assume you too. We can imagine most visual and mobility handicaps, but I, for one, have no way to anticipate the problems our designs might cause the dyslexic.
Dyslexia is not a single symptom disability. Designing for Dyslexics, by Mel Pedley, will straighten a lot of things out.